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The use of anabolic steroids has been linked to many forms of liver toxicity such as hepatic tumours and chronic vascular injury to the liver. The effects of steroids on brain function have been less studied, but it is thought that, like other drugs, they can cause cognitive dysfunction during periods of stress and anxiety . Many studies have looked at the effects of chronic use of anabolic steroids on the brain during cognitive testing. In the last few years it has been found that these drugs can cause disturbances in the function of the brain stem known as 'hypothalamus'   although this is much disputed, steroids online canada legit. The hypothalamus is located in the middle of the brain and controls energy balance, glucose regulation, mood and sleep and is also involved in circadian rhythm and other behavioural responses , anabolic steroids liver injury. During the testing sessions, participants were asked various questions about their memory and focus on a number of cognitive tasks as well as questions about their sleep and mood. Researchers found that steroids can impair cognitive learning and memory, and that they can affect the sleep-wake cycle affecting both daytime performance and the subsequent functioning of the brain (e, legal anabolic supplements australia.g, legal anabolic supplements australia. wakefulness and alertness) , legal anabolic supplements australia. Sleep deprivation has also been shown to have adverse effects on sleep and wake cycles in animals and humans . Stress Anabolic steroids also appear to have beneficial effects on the stress system, steroids anabolic liver injury. Steroids have a stimulating effect on the adrenal glands resulting in an increase in cortisol when they're taken , and this causes a lowering of the stress hormone corticosterone . This results in a weakening of the fight-or-flight response which then increases stress and anxiety . Corticosterone has anti-inflammatory properties  resulting in decreased skin pain after injury, pain relief when depressed or anxious, increased appetite , increased weight loss  and decreased acne. Anabolic steroids have analgesic properties  and are linked to reduced post traumatic stress disorder (PTSD), increased stress resilience, increased physical performance  and lowered anxiety , legal anabolic supplements australia. Anabolic athletes such as body builders and bodybuilders and athletes involved in high intensity sports are particularly vulnerable to the negative effects of steroids. In a 2004 study from Spain, it was found that anabolic steroid users had a significantly lower resting heart rate and significantly greater arterial blood pressure compared to non-users, best legal anabolic steroids for sale. Anabolic steroids can also cause an increase in heart rate and oxygen demand, as well as a decrease in blood glucose concentration.
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